7:45-8:45am
Join us for an engaging session featuring presentations from Thomas Jaki and Katherine (Kate) Lee.
All are welcome to join this session, though RSVPs are essential. A light breakfast and tea and coffee will be served. In person only.
9:00-10:05am
Rory Wolfe Opening address
James Matcham ICH E20: A New Era for Adaptive Designs in Clinical Development
Kert Viele Novel and emerging statistical designs for trials in rare diseases
Moderated Q&A
10:05-11:00am
The Debate: Modern approaches to trials for rare diseases have gone too far.
Chair: Tom Snelling
Speaking for the motion:
Liz Ryan
Julie Marsh
Speaking against the motion:
Kristy Robledo
Ian Marschner
11:00-11:25am
11:25am-12:50pm
Improving Trial Integrity: New Approaches to Design, Data Handling, and Outcome Measures
Speakers:
Tom Sullivan
Jessica Xu
Kylie Lange
Chris Selman
11:25am-12:50pm
Modern Statistical Methods for Clinical Trials in Action
Speakers:
Freda Werdiger
Gethmini Siriwardena
Francesca Orsini
Peixuan Li
12:50-1:40pm
During the lunch hour, come along to listen to our 5-minute poster presentations in the foyer.
1:40-3:05pm
Adaptive and Platform trials
Speakers
Trish Gilholm
Melissa Middleton
Rob Mahar
Michael Dymock
1:40-3:05pm
Innovations in Analysis for Complex Outcomes
Speakers
Gillian Heller
Kristy Robledo
Ding Ma
Leon Di Stefano
3:05-3:30pm
3:30-5:00pm
Chair: Kate Lee and Melissa Middleton
Steve Webb Current limitations of endpoints - how can we do better?
Charlie McLeod Co-designing outcome measures with those with lived experience - a clinician's perspective
Hannah Johns The win ratio: a novel approach for handling complex patient outcomes
Chris Selman Analysing ordinal outcome data with the proportional odds model
Thomas Jaki Dose-finding for combination treatments accounting for safety and activity with delayed outcomes
Panel discussion Melinda Cruz, Steve Webb, Charlie McLeod, Hannah Johns, Chris Selman, Thomas Jaki
5:00-6:00pm
All delegates are invited to join us for drinks and canapes in the venue foyer.
The price of the reception is included in your registration. RSVPs are essential when registering.
Full program available here